Posts tagged ‘NEJM’

Cirrosis Biliar Primaria

Primary biliary cirrhosis is a chronic, progressive cholestatic liver disease of unknown cause that usually affects middle-aged women and eventually leads to liver failure and the need for liver transplantation. It is diagnosed more frequently now than it was a decade ago because of its greater recognition by physicians and the widespread use of automated blood testing and the antimitochondrial-antibody test, which is relatively specific for the disease. Important advances have been made in our understanding of the natural history, pathogenesis, and treatment of primary biliary cirrhosis since the subject was last reviewed in the Journal. Little has changed in its pathological features, diagnosis, and clinical manifestations.

CBP

27 septiembre, 2010 at 18:27 Deja un comentario

Síndrome Antifosfolípido NEJM (Inglés)

ANTIPHOSPHOLIPID antibodies are a family  of  autoantibodies  that  exhibit  a  broad range of target specificities and affinities, all recognizing various combinations of phospholipids, phospholipid-binding  proteins,  or  both.  The  term
“antiphospholipid  syndrome” was  first coined  to denote the clinical association between antiphospholipid antibodies and a syndrome of hypercoagulability. Revision of the criteria for diagnosis of the antiphospholipid syndrome and the terminology used to describe the disease is an ongoing process

THE ANTIPHOSPHOLIPID SYNDROME. JERROLD S. LEVINE, M.D., D. WARE BRANCH, M.D., AND JOYCE RAUCH, PH.D.

Sindrome_Antifosfolipido_-__NEJM

14 febrero, 2010 at 0:56 Deja un comentario


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